In Alzheimer’s disease, glutamate excitotoxicity which can damage neurons through chronic activation is exacerbated by deficiency of ABCA7, the second strongest genetic risk factor for the disease. The findings highlight ABCA7 and glutamate–GABA signaling as potential therapeutic targets.

· · 来源:tutorial百科

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进一步分析发现,That principle underpins Billy Loo’s PHASER (Pluridirectional High-energy Agile Scanning Electron Radiotherapy) system, developed at Stanford and SLAC and licensed to a startup called TibaRay. An array of high-efficiency linacs generates X-ray beams from many directions at once. Their high output overcomes the inefficiency of electron-to-photon conversion to deliver the dose at FLASH speed. Beam convergence at the tumor and electronic shaping conform the dose in three dimensions, producing uniform coverage with relatively simple infrastructure.

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